OFFERED TOPICS

Visit us (room A131) or contact supervisors of the topics: Kvetoslav.Ruzicka@vscht, Michal.Fulem@vscht.cz, or Vojtech.Stejfa@vscht.cz. For PhD candidates, topics of the Dissertation can be selected upon discussion with us.

The offered topics are parts of the running projects:

• Ab initio mapping of phase behaviour of active pharmaceutical ingredients supported by accurate experimntal studies (LTAUSA18011)

• Rational design of drug delivery systems based on tailored biodegradable polymers using an iterative in silico and experimental approach (Czech Science Fundation GA_22-07164S, Principal investigator: Prof. M. Fulem, 2022-2024)

• Phase equilibrium and calorimetric study of clean diesel additives POME (polyoxymethylene dimethyl ethers) Details on Intranet
  
• Vapour pressure of fuel additives based on bioethanol and biobutanol Details on Intranet
  
• Contribution to a progressive method of CO2 removal from the atmosphere: thermodynamic study of selected diamines with aminocyclohexyl group Details on Intranet
  
• Sublimation pressures and enthalpies of selected organic substances occurring in interstellar space and in the outer region of the solar system Details on Intranet
• Determination of saturation vapour pressure of plasticizers (phthalates) and their safer alternatives (dialkyl triazole phthalates, and 1,2-cyclohexane dicarboxylic acid dialkyl esters) Details on Intranet
  
• Determination of saturation vapour pressures of polyaromatic hydrocarbons by a combination of static and chromatographic methods Details on Intranet
• Low-temperature calorimetry of polyaromatic hydrocarbons (PAHs)
• Thermodynamic study of solvents used in Li-ion batteries
• Thermodynamic study of industrially important solvent diphenyl carbonate
  
• Determination of heat capacities of biochemical model compounds
• Determination of saturation vapour pressure of environmentally relevant high boiling substances Details on Intranet

• Phase equilibrium studies of selected biochemical model compounds Details on Intranet

• Calculation of ideal-gas thermodynamic properties of biochemical model compounds using statistical thermodynamics and ab initio methods  Details on Intranet
• Calculation of thermodynamic properties of biochemical model compounds in the crystal phase using methods of theoretical chemistry  Details on Intranet
• A combined experimental and theoretical study of thermodynamic properties of selected API  Details on Intranet
• Vapour pressure and thermophysical properties of Chemical Warfare Agents simulants
• Experimental thermodynamic study of cubane and its derivatives Details on intranet
  
• Case study for theoretical ideal-gas thermodynamic properties of compounds with large-amplitude motions Details on intranet
• Phase behaviour and thermodynamic properties of racemic and enantiopure ibuprofen Details on intranet
• Thermodynamic properties and phase behaviour of active pharmaceutical ionic liquids Details on intranet

• Development of methods for studying extremely low vapor pressures Details on intranet
  

  
  

Topics of bachelor's and master's theses being solved in our laboratory:

• Determination of heat capacity of selected aliphatic hexanols (Hlib Lyshchuk, defended 2022 )
  
• Experimental screening of anticancer drug-biodegradable polymer compatibility (investigated by Martin Dinh)
• Influence of approximation of Gibbs energy of fusion on drug solubility description (Olga Vojtíšková, defended 2022)
• Thermodynamic properties and phase behaviour of ionic liquids (Štefan Kocian, defended 2022)
• Vapor pressure and thermophysical properties of nerve agent simulants (Aidana Piltan, defended 2022)
• Reconciliation of sublimation pressures of selected reference materials in the low-pressure region (Vladimír Pouzar, defended 2022)